Optimization of forming process of Zhuang medicine Luoqianyu cataplasm based on AHP-CRITIC method combined with star design

doi:10.14088/j.cnki.issn0439-8114.2024.04.026

HUBEI AGRICULTURAL SCIENCES ›› 2024, Vol. 63 ›› Issue (4): 141-147.doi: 10.14088/j.cnki.issn0439-8114.2024.04.026

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Optimization of forming process of Zhuang medicine Luoqianyu cataplasm based on AHP-CRITIC method combined with star design

XIE Meng-jiao^a, GUO Yong-xiu^a, LAI Xin-hong^a, LI Fang-chan^a, HUANG Yin^a, HUANG Ai-ai^a, WANG Ya-qin^a, HUANG Xue-ting^a, JIANG Lin^a,b

a. College of Pharmacy; b. Zhuang Yao Medicine Engineering Technology Center, Guangxi University of Chinese Medicine, Nanning 530001,China

Received:2021-12-27 Online:2024-04-25 Published:2024-05-07

Abstract

Abstract: Taking the initial viscosity, holding viscosity and comprehensive sensory evaluation as indexes, the weight of each index was determined by the AHP-CRITIC mixed weighting method, and the comprehensive score was calculated. The star design-response surface method was used to optimize the best forming process of Zhuang medicine Luoqianyu cataplasm. The results showed that the best blank matrix formulation of Zhuang medicine Luoqianyu cataplasm was NP-700 of 1.6 g, silica gel powder of 1.0 g, dihydroxyaluminum aminoacetate of 0.8 g, glycerol of 12.0 g, carbomer 940 of 0.5 g, CMC-Na of 0.5 g, EDTA-2Na of 26 mg, and deionized water of 10 mL. The preparation method was as follows： NP-700, silica gel powder and dihydroxyaluminum aminoacetate were swelled in glycerol as phase A, EDTA-2Na was dissolved in deionized water, carbomer 940 and CMC-Na were swelled as phase B, phase A was added into phase B to stir evenly, and the resulting blank matrix was mixed evenly with the prescribed cream. The optimized preparation process was stable and feasible, and the actual production was operable, which could be used for the preparation of Zhuang medicine Luoqianyu cataplasm.

Key words: Zhuang medicine Luoqianyu cataplasm, AHP-CRITIC, star design, forming process

CLC Number:

R283.6

XIE Meng-jiao, GUO Yong-xiu, LAI Xin-hong, LI Fang-chan, HUANG Yin, HUANG Ai-ai, WANG Ya-qin, HUANG Xue-ting, JIANG Lin. Optimization of forming process of Zhuang medicine Luoqianyu cataplasm based on AHP-CRITIC method combined with star design[J]. HUBEI AGRICULTURAL SCIENCES, 2024, 63(4): 141-147.

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Optimization of forming process of Zhuang medicine Luoqianyu cataplasm based on AHP-CRITIC method combined with star design

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