Abstract: In order to study the suitable planting conditions of Trichosanthes kirilowii, the cultivation experiments at different altitudes and densities were carried out. The growth cycle and seed yield of Trichosanthes kirilowii were statistically analyzed, and the benefit was analyzed in combination with the market purchase price. The results showed that it was not suitable for commercial Trichosanthes kirilowii cultivars to grow in the high altitude area. When the planting density was 3 000 plants/hm², the total input was lower, the comprehensive benefit was higher, the average seed yield was 1 375.5 kg/hm², and the net profit was 49 860 yuan/hm².

Key words: Trichosanthes kirilowii, altitude, planting density, yield