Application Research on the Safety Evaluation of Reconstituted Tobacco Products with Production Recycle-Water

doi:10.14088/j.cnki.issn0439-8114.2019.03.027

Abstract

Abstract: In order to study the safety of recycle-water produced by reconstituted tobacco production wastewater treatment and reuse systems for the safety of reconstituted tobacco products, in this paper, there were three in vitro toxicology tests,the bacterial reverse mutation assay（Ames test）,neutral red uptake assay, and in vitro micronucleus assay,which performed on reconstituted tobacco products produced from purified water. The results showed that the purified water reused after the zero discharge system of reconstituted tobacco production wastewater was suitable for the production of reconstituted tobacco products. The test results provide technical support for the industrial application of the zero discharge system of production wastewater.

Key words: reconstituted tobacco, recycle-water, safety evaluation, in vitro toxicology test

CLC Number:

S572
X795

XU Jiang-hong, YU Hong-tao, LIU Jian-ping, GUAN Ping, JI Song-yi, KUANG Zhi-min, WANG Hao-ya. Application Research on the Safety Evaluation of Reconstituted Tobacco Products with Production Recycle-Water[J]. HUBEI AGRICULTURAL SCIENCES, 2019, 58(3): 102-105.

References

[1] 马迅,殷艳飞,王浩雅,等.超声波协同Fenton氧化法去除造纸法再造烟叶废水COD[J].环境工程学报,2014(11):4752-4756.
[2] 王俊,孙莉莉,唐启,等.混凝-Fenton氧化工艺深度处理造纸法烟草薄片废水[J].河南科学,2014(12):2570-2573.
[3] 唐向阳,陆彦兵,杨斌,等.微纳米气浮处理造纸法烟草薄片废水试验研究[J].新技术新工艺,2012(9):49-50.
[4] 陈荣. 造纸法烟草薄片生产废水的处理[J].环境科学导刊,2010(1):68-70.
[5] 米其利,唐萍,倪红梅,等.溶剂对卷烟烟气气相物捕集和细胞毒性检测的影响[J].云南大学学报(自然科学版),2010,32(S1):134-138.
[6] 管莹,李雪梅,米其利,等.Ames试验重要影响因素研究[J].化学与生物工程,2017,34(11):35-39.
[7] 苏彬. 烟草种子油的毒理学评价及降脂功能研究[D].山东青岛:青岛大学,2016.
[8] 黄龙. 天然植物提取物在烟草中的应用及其毒理学评价[A].湖北省烟草学会2006年学术年会论文集[C].武汉:湖北省烟草学会,2006.
[9] 苏彬,傅泳,侯小东,等.烟草种子油的毒理学评价[J].癌变·畸变·突变,2016,28(1):60-65.
[10] 李翔,谢复炜,刘惠民.新型烟草制品毒理学评价研究进展[J].烟草科技,2016,49(1):88-93.
[11] 张帅,寇霄腾,张相辉,等.烟用香精香料安全性影响因素及控制措施研究[J].农产品加工,2017(17):61-63.
[12] 李源,韩亚伟,张东鹏,等.烟用添加剂生物学评价技术进展[J].农产品加工,2018(2):59-61.
[13] 王琴美,蓝勤娴,吴嘉彤,等.部分国产烤烟型卷烟烟气冷凝物的中性红细胞毒性试验[J].烟草科技,2007(5):41-43.
[14] GB 15193-2003,食品安全性毒理学评价程序[S].
[15] YY/T0127.10-2009,口腔医疗器械生物学评价第2单元:试验方法鼠伤寒沙门氏杆菌回复突变试验(Ames试验)[S].
[16] GB7919-87,化妆品安全性评价程序和方法[S].
[17] GB 15670-1995,农药登记毒理学试验方法[S].
[18] CJ/T 150-2001,城市供水水质检验方法标准及编制说明和研究报告[S].
[19] MORTELMANS K,ZEIGER E.The Ames/microsome mutage-nicity assay[J].Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis,2000,455(1/2):29-60.
[20] 黄海涛,管莹,周岚,等.卷烟烟气中性红细胞毒性试验不确定度评定[J].化学与生物工程,2012,29(11):68-70.
[21] 管莹,高茜,朱洲海,等.体外微核试验重要影响因素研究[J].化学与生物工程,2013,30(2):64-66.