HUBEI AGRICULTURAL SCIENCES ›› 2022, Vol. 61 ›› Issue (3): 117-120.doi: 10.14088/j.cnki.issn0439-8114.2022.03.024

• Animal Husbandry & Veterinary Medicine • Previous Articles     Next Articles

Animal experimental study on Wuwei Quzhi Granules as an adjuvant therapy in reducing blood lipid

LI Fang-chan1,2, WEI Hong-qin1, CHEN Qing1,2, LUO Yu-dong3, PANG Xiao-yun3, HUANG Jing1, WANG Su-fei1   

  1. 1. Guangxi University of Chinese Medicine, Nanning 530200, China;
    2. Guangxi Zhuang Yao Medicine Center of Engineering and Technology, Nanning 530200, China;
    3. Pharmaceutical Factory, Guangxi University of Chinese Medicine, Nanning 530000, China
  • Received:2021-03-08 Online:2022-02-10 Published:2022-03-11

Abstract: To study the hypolipidemic effect of Wuwei Quzhi Granules on hyperlipemia rats through auxiliary hypolipidemic animal experimental study, hyperlipidemia model rats was established by feeding high fat diet. 40 hyperlipidemia model rats were randomly divided into model control group, fenofibrate group and the Wuwei Quzhi Granules low, medium and high dose group. The corresponding test substance were given once a day for 30 days. Blood was taken from the inner canthus of eyes, and TC, TG, LDL-C, HDL-C in rats were observed. The result shows that compared with the model control group, TC, TG, LDL-C in the Wuwei Quzhi Granules low, medium and high dose group increased with the increase of the dose, the difference between the medium and high dose groups was significant (P<0.05 or P<0.01), TG in the Wuwei Quzhi Granules low dose group increased with a significant difference (P<0.05). HDL-C in the Wuwei Quzhi Granules low, medium and high dose group had statistically significant difference (P<0.05 or P<0.01). Wuwei Quzhi Granules has the functions of the adjuvant therapy in reducing blood lipid.

Key words: Wuwei Quzhi Granules, reducing blood lipid, lose weight

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