Study on intestinal absorption characteristics of astaxanthin extracted from Solenocera crassicornis

doi:10.14088/j.cnki.issn0439-8114.2021.20.027

Abstract

Abstract: The Sprague Dawley male rats were given a single high-dose gavage with saponified and unsaponified astaxanthin, the content of astaxanthin in different parts of the small intestine after 6 h and 12 h were determined, and the total content of astaxanthin, free astaxanthin and ester astaxanthin in fresh feces of rats after 14 d of continuous gavage were detected by HPLC. The results showed that after 6 h of gavage,astaxanthin was not detected in the jejunum, ileum and colon of rats. After 12 h of gavage, astaxanthin was detected in the colon contents of both the saponified and unsaponified astaxanthin group, and the content of astaxanthin in the saponified group （283.221±89.50 μg/g） was significantly higher than that in the unsaponified group （126.850±40.49 μg/g）. After 14 d of continuous gavage, the astaxanthin residue from in feces of rats in the saponified group was significantly lower than that in the unsaponified group, and the astaxanthin residue was mainly composed of free astaxanthin（11.12±0.36 μg/g）. However, the contents of free astaxanthin and ester astaxanthin in the rats feces of unsaponified group were 21.78±3.40 μg/g and 7.69±0.32 μg/g, respectively. Therefore, the saponified astaxanthin derived from Solenocera crassicornis showed better intestinal absorption compared with the unsaponified astaxanthin.

Key words: Solenocera crassicornis, astaxanthin, intestinal absorption, free astaxanthin, ester astaxanthin

CLC Number:

TS254.9

JIA Zhe, XU Yan, LIU Xin-yan, ZHANG Xiao-xia, SONG Ru. Study on intestinal absorption characteristics of astaxanthin extracted from Solenocera crassicornis[J]. HUBEI AGRICULTURAL SCIENCES, 2021, 60(20): 134-138.

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