湖北农业科学 ›› 2019, Vol. 58 ›› Issue (20): 118-120.doi: 10.14088/j.cnki.issn0439-8114.2019.20.028

• 畜牧·兽医 • 上一篇    下一篇

广西甜茶醇提物对小鼠血糖及糖耐量的影响

蒙淑洁1,2, 闫志刚2, 徐永莉2, 吴庆华2, 冯世鑫2, 李力1,2   

  1. 1.广西医科大学,南宁 530021;
    2.广西药用植物园,南宁 530023
  • 收稿日期:2019-01-14 出版日期:2019-10-25 发布日期:2019-11-19
  • 通讯作者: 李 力(1963-),男,四川成都人,研究员,研究方向为中药资源保护及利用研究,(电子信箱)Liboshi1963@vip.163.com。
  • 作者简介:蒙淑洁(1992-),女,广西宁明人,在读硕士研究生,研究方向为药物化学及药理研究,(电话)18577179587(电子信箱)396567265@qq.com;
  • 基金资助:
    广西重点研发计划项目(桂科AB16380346); 2015年生态广西建设引导资金项目[桂财建函(2015)87号文]

Effects of ethanol extract of Rubus suavissimus S. Lee on blood sugar and glucose tolerance in mice

MENG Shu-jie1,2, YAN Zhi-gang2, XU Yong-li2, WU Qing-hua2, FENG Shi-xin2, LI Li1,2   

  1. 1.Guangxi Medical University,Nanning 530021,China;
    2.Guangxi Botanical Garden of Medicinal Plants,Nanning 530023,China
  • Received:2019-01-14 Online:2019-10-25 Published:2019-11-19

摘要: 为研究广西甜茶(Rubus suavissimus S. Lee)醇提物对小鼠血糖及糖耐量的影响,分为空白组、广西甜茶醇提物高、中、低(250、150、100 g/kg)等4组剂量组,对小鼠连续灌胃给药40 d,观察其对小鼠血糖的影响。结果表明,广西甜茶醇提物低剂量组(P<0.01)和中剂量组(P<0.05)对小鼠空腹血糖有显著影响,并随着给药时间的延长,对葡萄糖致小鼠高血糖有一定的抑制作用,与空白对照组相比低剂量组和中剂量组给药40 d后体重明显降低。

关键词: 广西甜茶(Rubus suavissimus S. Lee), 醇提物, 空腹血糖, 糖耐量, 体重

Abstract: To study the effects of ethanol extract of Rubus Suavissimus S. Lee on blood sugar and glucose tolerance in mice. KM mice were divided into four dosage groupsblank group, high, medium and low ethanol extracts of sweet tea from Rubus suavissimus S. Lee(250,150,100 g/kg). The effects of ethanol extracts on blood sugar in normal mice were observed after 40 days of continuous intragastric administration. The results showed that low-dose group(P<0.01) and middle-dose group (P<0.05) of ethanol extract of Rubus suavissimus S. Lee had significant effects on fasting blood glucose in mice, and with the increase of administration time, they had certain inhibitory effects on hyperglycemia induced by glucose in mice. Compared with the blank control group, the body weight of low-dose group and middle-dose group after 40 days of administration was significant markedly reduced.

Key words: sweet tea (Rubus suavissimus S. Lee), ethanol extract, fasting blood glucose, glucose tolerance, body weight

中图分类号: