Argonaute蛋白结构及其在植物中的研究进展

doi:10.14088/j.cnki.issn0439-8114.2020.08.002

摘要/Abstract

摘要： 在真核细胞中,许多小的非编码RNA与Argonaute蛋白结合形成RNA诱导沉默复合体,并通过识别互补的靶标RNA来调控基因表达,此过程叫RNA干扰。在植物的RNA干扰途径中,Argonaute-sRNA复合物可以通过多种不同的机制发挥作用,进而参与病原体防御、植物发育调控等关键的生物过程。综述了Argonaute蛋白的分类和结构特征、在植物体中参与RNA干扰的机制及生物学功能等研究进展。

关键词: Argonaute蛋白, 结构, RNA干扰, 功能

Abstract: In eukaryotic cells, many small non-coding RNAs combind with Argonaute protein to form the RNA-induced silencing complex, the Argonaute-sRNA can regulate gene expression by recognizing complementary RNA targets, which is called RNA interference. Argonaute-sRNA complexcan play interfering roles via multiply mechanisms in plants, and then participate in key biological processes such as pathogen defense and developmental regulation. Here, we review the classification and structural characteristics of Argonaute protein, as well as mechanisms of RNA interference and biological functions on Argonaute in plants.

Key words: Argonaute protein, structure, RNA interference, function

中图分类号:

谷少伟. Argonaute蛋白结构及其在植物中的研究进展[J]. 湖北农业科学, 2020, 59(8): 11-16.

GU Shao-wei. The structure of Argonaute protein and research progress in plants[J]. HUBEI AGRICULTURAL SCIENCES, 2020, 59(8): 11-16.

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