真菌NBERC-170301中农药活性化合物的研究

doi:10.14088/j.cnki.issn0439-8114.2018.22.017

湖北农业科学 ›› 2018, Vol. 57 ›› Issue (22): 60-63.doi: 10.14088/j.cnki.issn0439-8114.2018.22.017

真菌NBERC-170301中农药活性化合物的研究

张亚妮, 方伟, 王开梅, 张志刚, 王燕, 万中义, 吴兆圆

湖北省生物农药工程研究中心/湖北省农业科技创新中心生物农药分中心,武汉 430064

收稿日期:2018-07-30 出版日期:2018-11-25 发布日期:2019-12-19
通讯作者: 吴兆圆（1985-）,女,湖北石首人,助理研究员,（电话）15102708891（电子信箱）zhaoyuan.wu@nberc.com。
作者简介:张亚妮（1979-）,女,陕西眉县人,助理研究员,硕士,主要从事天然产物分离纯化研究,（电话）18627922090（电子信箱）yani.zhang@nberc.com
基金资助:
国家重点研发项目（2017YFD0201205）; 湖北省技术创新专项重大项目（2016ABA103）; 湖北省农业科技创新中心创新团队项目（2016-620-000-001-039）

Study on the Pesticide Activity Compounds from Fungus NBERC-170301

ZHANG Ya-ni, FANG Wei, WANG Kai-mei, ZHANG Zhi-gang, WANG Yan, WAN Zhong-yi, WU Zhao-yuan

Hubei Biopesticide Engineering Research Center/The Branch Center of Biopesiticide,Hubei Agricultural Scientific and Technological Innovation Center,Wuhan 430064,China

Received:2018-07-30 Online:2018-11-25 Published:2019-12-19

摘要/Abstract

摘要： 筛选到一株具有农药活性的真菌NBERC-170301,通过活性跟踪,确定出其中的活性组分。并经过大量发酵,提取分离得到4个化合物,经超高效液质联用（UPLC-MS）和NMR确定其中3个化合物分别为青霉酸、郝金青霉素和郝青霉素酮,活性测试结果表明,化合物4对小菜蛾具有较好的毒杀活性,但结构暂未确定。

关键词: 真菌NBERC-170301, 农药活性, 青霉酸, 郝金青霉素, 郝青霉素酮

Abstract: Fungus NBERC-170301 which had pesticide activity was found. By active tracking,the active fractions were detected,and 4 compounds were obtained（1-4）. Compounds 1-3 were identified as penicillic acid（1）,herqueichrysin（2） and herqueinone（3） by UPLC-MS and NMR. The results of biological activity showed that compound 4 had insecticidal activity against the Plutella xylostella L.,however,the structure of which was failed to be identified.

Key words: fungus NBERC-170301, pesticide activity, penicillic acid, herqueichrysin, herqueinone

中图分类号:

TQ450.1

张亚妮, 方伟, 王开梅, 张志刚, 王燕, 万中义, 吴兆圆. 真菌NBERC-170301中农药活性化合物的研究[J]. 湖北农业科学, 2018, 57(22): 60-63.

ZHANG Ya-ni, FANG Wei, WANG Kai-mei, ZHANG Zhi-gang, WANG Yan, WAN Zhong-yi, WU Zhao-yuan. Study on the Pesticide Activity Compounds from Fungus NBERC-170301[J]. HUBEI AGRICULTURAL SCIENCES, 2018, 57(22): 60-63.

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真菌NBERC-170301中农药活性化合物的研究

Study on the Pesticide Activity Compounds from Fungus NBERC-170301

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